Original Article

DETECTION OF GENE MUTATION IN SPUTUM OF LUNG CANCER PATIENT

He-long Zhang, Wen-liang Wang, Da-xiang Cui

Abstract

Lung cancer is a common malignant tumor, which has a high incidence and mortality rate. Therefore, it is necessary to seek a new method for the diagnosis, especially the early diagnosis of lung cancer. The development of molecular biology makes the gene diagnosis of lung cancer possible. PCR-SSCP was applied to detect p53 gene mutation of lung cancer patients' sputum cells and we have achieved good results.