Original Article


HIGH DOSE FRACTION RADIOTHERAPY FOR MUCOSAL MALIGNANT MELANOMA OF THE HEAD AND NECK

Xiuying Liu, Huiling Li, Tianrong Zheng, Xiangsong Lin

Abstract

Objective: To evatuate the results of high dose fraction radiotherapy for mucosal malignant melanoma of the head and neck (HNMM).
Methods: From 1984-1994, 35 patients with HNMM were enrolled in this study. Among them, 27 cases localized to the nasal cavity or para-nasal sinus, 8 to the oral cavity. All patients received high dose fraction radiotherapy (6-8 Gy/fraction) with the total dose ranged from 40 to 60 Gy.
Results: The minimum follow-up was 2 years (ranged 2-7 years). The overall 3- and 5-year survival rate was 45.7% and 24%, respectively.
Conclusion: High dose fraction radiotherapy is effective for local control of HNMM.