@article{CJCR903,
author = {Juan Wei and Lian-ke Liu and Wen Gao and Cheng-jun Zhu and Yi-qian Liu and Ting Cheng and Yong-qian Shu},
title = {Reduction of Plasma MicroRNA-21 is Associated with Chemotherapeutic Response in Patients with Non-small Cell Lung Cancer},
journal = {Chinese Journal of Cancer Research},
volume = {23},
number = {2},
year = {2012},
keywords = {},
abstract = {Objective: To examine plasma microRNA-21 (miR-21) level in patients with non-small cell lung cancer (NSCLC) and its potential correlation with chemotherapeutic response.
Methods: 77 NSCLC patients and 36 age and sex-matched healthy controls were included. Plasma miR-21 concentration was examined using a quantitative real-time reverse transcription polymerase chain reaction assay (qRT-PCR). Potential correlation between plasma mir-21 concentrations with chemotherapeutic responses was analyzed in 35 patients with advanced NSCLC (stages IIIB and IV).
Results: Plasma miR-21 was significantly higher in NSCLC patients relative to the healthy controls (P},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/903}
}