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Caveolin-1, E-cadherin and β-catenin in Gastric Carcinoma, Precancerous Tissues and Chronic Non-atrophic Gastritis

  
@article{CJCR807,
	author = {Guo-yang Sun and Jun-xia Wu and Jian-sheng Wu and Yu-ting Pan and Rong Jin},
	title = {Caveolin-1, E-cadherin and β-catenin in Gastric Carcinoma, Precancerous Tissues and Chronic Non-atrophic Gastritis},
	journal = {Chinese Journal of Cancer Research},
	volume = {24},
	number = {1},
	year = {2012},
	keywords = {},
	abstract = {Objective: To investigate the expressions of caveolin-1, E-cadherin and β-catenin in gastric carcinoma, precancerous gastric and chronic non-atrophic gastritis tissues, and evaluate the correlation of these expressions with the development of gastric cancer.
Methods: The expressions of caveolin-1, E-cadherin and β-catenin were detected by biotin-streptavidinperoxidase (SP) immunohistochemistry on 58 gastric cancer tissues, 40 precancerous gastric tissues and 42 chronic non-atrophic gastritis tissues. The correlation between the expressions of caveolin-1, E-cadherin and β-catenin, and the clinicopathologic parameters of gastric cancer was analyzed retrospectively.
Results: The positive rates of caveolin-1 and E-cadherin expressions in gastric carcinoma were significantly lower than precancerous gastric and chronic non-atrophic gastritis tissues (P},
	issn = {1993-0631},	url = {https://cjcr.amegroups.org/article/view/807}
}