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Overexpression of HOXB9 promotes metastasis and indicates poor prognosis in colon cancer

  
@article{CJCR3345,
	author = {Kai Huang and Rongfa Yuan and Kai Wang and Junwen Hu and Zixi Huang and Chen Yan and Wei Shen and Jianghua Shao},
	title = {Overexpression of HOXB9 promotes metastasis and indicates poor prognosis in colon cancer},
	journal = {Chinese Journal of Cancer Research},
	volume = {26},
	number = {1},
	year = {2014},
	keywords = {},
	abstract = {Objective: Homeobox B9 (HOXB9) is proposed to be involved in tumor angiogenesis and metastasis. We investigated the role of HOXB9 in the progression of colon cancer.
Methods: HOXB9 expression was investigated by immunohistochemically and Western blotting in 128 colon cancer patients and the results were analyzed statistically associated with clinicopathological data and survival of the patients. The effect of HOXB9 on cell invasion and metastases abilities were analyzed in vitro and in vivo.
Results: HOXB9 is overexpressed in colon cancer tissues and significantly correlated with metastasis and poor survival of patients (P},
	issn = {1993-0631},	url = {https://cjcr.amegroups.org/article/view/3345}
}