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Spectral CT imaging as a new quantitative tool? Assessment of perfusion defects of pulmonary parenchyma in patients with lung cancer

  
@article{CJCR3077,
	author = {Ying-Shi Sun and Xiao-Yan Zhang and Yong Cui and Lei Tang and Xiao-Ting Li and Ying Chen and Xiao-Peng Zhang},
	title = {Spectral CT imaging as a new quantitative tool? Assessment of perfusion defects of pulmonary parenchyma in patients with lung cancer},
	journal = {Chinese Journal of Cancer Research},
	volume = {25},
	number = {6},
	year = {2013},
	keywords = {},
	abstract = {Objective: This study investigated the capability of dual-energy spectral computed tomography (CT) to quantitatively evaluate lung perfusion defects that are induced by central lung cancer.
Methods: Thirty-two patients with central lung cancer underwent CT angiography using spectral imaging. A univariate general linear model was conducted to analyze the variance of iodine concentration/CT value with three factors of lung fields. A paired t-test was used to compare iodine concentrations and CT values between the distal end of lung cancer and the corresponding area in the contralateral normal lung.
Results: Iodine concentrations increased progressively in the far, intermediate and near ground sides in the normal lung fields at 0.60±0.28, 0.93±0.27 and 1.25±0.38 mg/mL, respectively (P},
	issn = {1993-0631},	url = {https://cjcr.amegroups.org/article/view/3077}
}