@article{CJCR2020,
author = {Weiqun Xiao},
title = {THE EXPRESSION OF CDK4 GENE IN HUMAN BREAST CANCER},
journal = {Chinese Journal of Cancer Research},
volume = {9},
number = {2},
year = {2013},
keywords = {},
abstract = {Purpose: To analyze the genetic changes of CDK4 gene and expression of CDK4 mRNA in the breast ganger.
Materials and methods: We obtained a fragment of CDK4 gene, from many kinds of human cancer or normal tissues by PCR .Taking it as a probe, using the methods of Southern and Dot blotting, we analyzed the role of CDK4 gene in the occurrence and development of human breast cancer.
Results: CDK4 gene appeared amplification and its mRNA overexpressed clearly in the breast cell line(MDA231). In human breast cancer tissues, CDK4 mRNA expressed much more than normal breast tissues(p},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/2020}
}