@article{CJCR1969,
author = {Wentao Yang and Liangzhong Xu and Taiming Zhang and weiping Zhu and Xiaomei Li and Aiping Jin},
title = {DETECTION OF TELOMERASE ACTIVITY IN BREAST CARCINOMA},
journal = {Chinese Journal of Cancer Research},
volume = {10},
number = {4},
year = {2013},
keywords = {},
abstract = {Objective: To investigate the significance of telomerase activity in breast carcinoma with its respect to axillary lymph node status.
Methods: Telomerase activity was analyzed in 88 breast carcinomas and 16 benign breast lesions, using polymerase chain reaction (PCR)-based telomeric repeat amplification protocol (TRAP) assay.
Results: Telomerase activity was detected in 75 (85%) of 88 breast carcinomas (including three breast carcinomas in situ which were all positive for telomerase activity), whereas in benign breast lesions analyzed only 2(12.5%) of 16 cases were positive for telomerase activity. The difference between the two groups was statistically significant (P},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/1969}
}