@article{CJCR1797,
author = {Huilan Zeng and Xueguang Zhang and Zixing Chen and Ruifang Tao and Yuehua Qiu and Yi Zhang and Aining Sun and Aiqing Wang and Wei Wang and Baojue Lin},
title = {EXPRESSION OF IL-6, sgp130, IL-8 AND THEIR RECEPTORS IN ACUTE PROMYELOCYTIC LEUKEMIA DURING ALL-TRANS RETINOIC ACID INDUCTION TREATMENT},
journal = {Chinese Journal of Cancer Research},
volume = {11},
number = {4},
year = {2013},
keywords = {},
abstract = {Objective: To evaluate the expression and its clinical significance of interleukin 6 (IL-6), soluble glyeoprotein 130 (sgp130), inlerleukin 8 (IL-8) and type A interlenkin 8 receptor (IL-8RA) in acute promyelocytic leukemia (APL) patients during all-trans retinoic acid (ATRA) induction treatment.
Methods: Plasma and bone marrow mononuclear cell (MNC) culture supernatant IL-6, sgpl30, IL-8 concentration of 18 cases with APL were kinetically measured in vivo and in vitro (ELISA). Bone marrow MNC IL-8RA was measured by flow eytometry after being cultured with ATRA (10-6mmol/L).
Results: Plasma IL-6, sgp130, IL-8 levels were higher than normal (P},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/1797}
}