@article{CJCR1646,
author = {Juan Li and Xianhui Ren and Zhaowei Huang and Yueying Jin and Zihui Wang and EC Chew},
title = {NUCLEAR MATRIX PROTEIN IN LEUKEMIA CELLS},
journal = {Chinese Journal of Cancer Research},
volume = {11},
number = {2},
year = {2013},
keywords = {},
abstract = {Objective: To compare the composition of nuclear matrix proteins (NMP) between leukemia cells and normal bone marrow cells.
Methods: NMP was isolated by high-salt extraction and identified in acute and chronic myelogenous leukemia cells as well as in the blast phase of chronic leukemia. On SDS-PAGE, NMPs with molecular myelogenous ferment from what were seen in normal bone marrow cells were present in both acute and chronic myelogenous leukemia.
Conclusion: Marked changes of NMP, not only in contents but also in compositions, exist in leukemic cells compared with normal bone marrow cells. NMP may serve as a target of chemotherapeutic drug against leukemia.},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/1646}
}