TY  - JOUR
AU  - Li, Yan
AU  - Bai, De-jiao
AU  - Wang, Kun
AU  - Yang, Guo-liang
AU  - Yuan, Hong-yin
AU  - Shao, Hua
PY  - 2013
TI  - EFFECTS OF PERIOPERATIVE CIMETIDINE ADMINISTRATION ON NATURAL KILLER CELLS IN PATIENTS WITH GASTROINTESTINAL CANCER
JF  - Chinese Journal of Cancer Research; Vol 11, No 1 (March 11, 1999): Chinese Journal of Cancer Research
Y2  - 2013
KW  - 
N2  - Objective: To study the effects of perioperative use of cimetidine on natural killer (NK) cells in gastrointestinal (GI) cancer patients.   Methods: 49 GI cancer patients were randomized into treatment group which took cimetidine in the perioperative period, and control group which did not take the drug. NK cells were measured by immunocytochemical method, using mouse-anti-human CD57 monoclonai antibody as the primary antibody. Blood samples from 20 healthy volunteers were treated in the same way as normal control. Comparisons were made within and between groups.   Results: The NK cell percentage of normal control was 18.50±12.31. Both groups of patients had significantly lower than normal NK percentages before treatment (P
UR  - https://cjcr.amegroups.org/article/view/1625