@article{CJCR1625,
author = {Yan Li and De-jiao Bai and Kun Wang and Guo-liang Yang and Hong-yin Yuan and Hua Shao},
title = {EFFECTS OF PERIOPERATIVE CIMETIDINE ADMINISTRATION ON NATURAL KILLER CELLS IN PATIENTS WITH GASTROINTESTINAL CANCER},
journal = {Chinese Journal of Cancer Research},
volume = {11},
number = {1},
year = {2013},
keywords = {},
abstract = {Objective: To study the effects of perioperative use of cimetidine on natural killer (NK) cells in gastrointestinal (GI) cancer patients.
Methods: 49 GI cancer patients were randomized into treatment group which took cimetidine in the perioperative period, and control group which did not take the drug. NK cells were measured by immunocytochemical method, using mouse-anti-human CD57 monoclonai antibody as the primary antibody. Blood samples from 20 healthy volunteers were treated in the same way as normal control. Comparisons were made within and between groups.
Results: The NK cell percentage of normal control was 18.50±12.31. Both groups of patients had significantly lower than normal NK percentages before treatment (P},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/1625}
}