@article{CJCR1624,
author = {Xiu-ying Liu and Hui-Ling Li and Tian-rong Zheng},
title = {LONG TERM RESULTS OF BRONCHIAL ARTERIAL INFUSION WITH CHEMOTHERAPEUTIC AGENTS PLUS RADIATION THERAPY IN THE TERATMENT OF LOCALLY ADVANCED NON SMALL CELL LUNG CANCER},
journal = {Chinese Journal of Cancer Research},
volume = {11},
number = {1},
year = {2013},
keywords = {},
abstract = {Objective: To evaluate the efficacy of the bronchial arterial infusion (BAI) plus radiation therapy (RT) for locally advanced non-small-cell lung cancer (NSCLC).
Methods: 79 patients.with locally advanced NSCLC were divided randomly into two groups. In the RT group, the radiation was given by 8Mv X-ray or 18Mv X-ray .with 2Gy/fraction, 5 fraction per week with a total dose of 60Gy-65Gy/6-7 weeks. In the BAI+RT group, the radiation was given as RT group. Bronchial arterial infusion was performed before RT. The regimen consisted of DDP 100 mg/m2, MMC 10 rag, and 5-Fu 1000 mg. Each patient received two or three cycles.
Results: The overall response rates were 80.5% in BAI+RT group and 50% in RT group. The 1-, 3-, 5-year survival rates in the BAI+RT group were significantly improved when compared to the RT group, being 87.8% vs 36.8%, 39.0% vs 7.9%, and 17.1% vs 2.6% respectively. The median time of radiation treatment to recurrence of primary lesion was 11 months in the BAI+RT group and 5 months in the RT group (P},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/1624}
}