@article{CJCR1573,
author = {Ke-chen Ban and Jian-jia Su and Chun Yang and Liu-liang Qin and Yuan Li and Guo-hua Huang and Xiao-ling Luo and Xiao-xian Duan and Rui-qi Yan},
title = {EXPRESSION OF ras GENE IN EXPERIMENTAL HEPATOCARCINOGENESIS IN TREE SHREWS},
journal = {Chinese Journal of Cancer Research},
volume = {11},
number = {1},
year = {2013},
keywords = {},
abstract = {Objective: In order to investigate the relationship between the expression of ras gene and the development of hepatocellular carcinoma (HCC). Materials and
Methods: The experimental tree shrews were divided into four groups: group A, infected human hepatitis B virus (HBV) and exposed to aflatoxin B1 (AFB1); group B, infected human HBV alone; group C, only exposed to AFB1; group D, use as controls. The serial bioptic liver tissues were detected for ras p21 protein using immunohistochemical method.
Results: The total p21 protein positive rates in group A, B, C and D were 35.3%, 5.3%, 13.3%, 0, respectively, thus the significant difference were showed between group A and group B (P},
issn = {1993-0631}, url = {https://cjcr.amegroups.org/article/view/1573}
}